Fate of the DnaA initiator protein in replication at the origin of the Escherichia coli chromosome in vitro.
![Frontiers | The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC Frontiers | The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC](https://www.frontiersin.org/files/MyHome%20Article%20Library/401496/401496_Thumb_400.jpg)
Frontiers | The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC
DnaA protein directs the binding of DnaB protein in initiation of DNA replication in Escherichia coli.
DnaA protein directs the binding of DnaB protein in initiation of DNA replication in Escherichia coli.
![The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase: Cell The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase: Cell](https://www.cell.com/cms/attachment/e4f54112-808e-4e8e-b2e3-1cd6c2ad08f3/gr6_lrg.jpg)
The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase: Cell
![The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase: Cell The Initiator Function of DnaA Protein Is Negatively Regulated by the Sliding Clamp of the E. coli Chromosomal Replicase: Cell](https://www.cell.com/cms/attachment/7772f97d-1d8c-403a-8ed1-c90893560c80/gr1_lrg.jpg)